Table 4

Baseline scores of inflammatory markers in epithelium and lamina propria of biopsy specimens taken from the central airways of smoking patients with COPD and healthy smoking control subjects

EpitheliumLamina propria
MarkerPatients with COPDHealthy smoking controlsPatients with COPDHealthy smoking controls
Data are expressed as median (range) ratios of immunostained areas and field measurement which consisted of the total area of either the epithelium or the lamina propria. Statistical analysis by Mann-Whitney U test after log transformation.
CD30.72 (0.10–4.52)0.63 (0.24–0.93)0.36 (0.04–5.71)0.74 (0.61–1.19)
CD41.07 (0.14–4.00)0.94 (0.40–2.00)0.74 (0.07–9.00)0.64 (0.27–1.63)
CD80.08 (0.03–0.60)0.05 (0.02–0.09)0.04 (0.03–0.42)0.04 (0.01–0.13)
CD250.22 (0.03–3.28)0.10 (0.03–0.22)0.15 (0.03–2.39)0.12 (0.04–0.26)
MBP0.12 (0.03–5.27)0.03 (0.01–0.67)0.38 (0.00–6.45)0.25 (0.01–5.13)
EG20.12 (0.01–1.79)0.12 (0.01–0.55)0.25 (0.03–0.68)0.46 (0.14–8.01)
CD153.43 (0.08–17.4)3.39 (0.68–8.96)0.62 (0.14–4.73)0.81 (0.01–1.40)
CD681.53 (0.24–11.4)1.09 (0.46–1.98)2.49 (0.44–20.10)2.95 (1.13–4.74)
CD1a0.12 (0.04–0.45)0.08 (0.03–0.18)0.14 (0.04–0.35)0.07 (0.02–0.12)
Tryptase0.14 (0.03–0.63)0.10 (0.05–0.29)1.30 (0.12–4.03)1.23 (0.20–2.49)