Clinical characteristics of study subjects
| Healthy non-atopic controls (n=6) | Asthma (n=8) | COPD (n=7) | |
|---|---|---|---|
| Results expressed as mean (SE). | |||
| FEV1=forced expiratory volume in 1 second; FVC=forced vital capacity; PC20=concentration provoking a fall in FEV1 of 20% or more; N/A=not applicable. | |||
| Age (years) | 31.1 (1.2) | 30.9 (2.2) | 63.1 (4.2) |
| Sex (F/M) | 4/2 | 5/3 | 0/8 |
| FEV1 (% predicted) | 96.6 (4.1) | 90.8 (4.5) | 55.1 (5.9) |
| PC20 (mg/ml) | N/A | 1.4 (0.5) | N/A |
| Current smokers (%) | 0.0 | 0.0 | 62.5 |
| Pack years | 0.0 | 0.0 | 52.6 (5.3) |
| FEV1/FVC ratio | 77.8 (3.6) | 87.7 (3.3) | 55.5 (5.9) |
| Drugs | Nil | β2 agonist ×1/week | 3 nil, 1 β2 agonist only, 3 on >400 μg BDP |