Mean* (SE) nocturnal forced vital capacity (FVC) and overall steady state FVC differences between treatment groups after 6 weeks of study drug
| Treatment | Mean (SE) | Comparison | Difference (SE) | p value | 95% CI |
|---|---|---|---|---|---|
| *Means are adjusted for centre and baseline. | |||||
| Nocturnal FVC | |||||
| AM | 1.99 (0.05) | AM – Placebo | 0.31 (0.07) | 0.0001 | (0.18 to 0.45) |
| PM | 2.02 (0.05) | PM – Placebo | 0.35 (0.07) | 0.0001 | (0.22 to 0.48) |
| Placebo | 1.68 (0.05) | AM – PM | −0.03 (0.07) | 0.6051 | (−0.16 to 0.10) |
| Steady state FVC | |||||
| AM | 2.12 (0.04) | AM – Placebo | 0.32 (0.06) | 0.0001 | (0.21 to 0.44) |
| PM | 2.07 (0.04) | PM – Placebo | 0.27 (0.06) | 0.0001 | (0.16 to 0.39) |
| Placebo | 1.79 (0.04) | AM – PM | 0.05 (0.06) | 0.3526 | (−0.06 to 0.16) |