Mean* (SE) nocturnal forced expiratory volume in 1 second (FEV1) and overall steady state FEV1 differences between treatment groups after 6 weeks of study drug
| Treatment | Mean (SE) | Comparison | Difference (SE) | p value | 95% CI |
|---|---|---|---|---|---|
| *Means are adjusted for centre and baseline. | |||||
| Nocturnal FEV1 | |||||
| AM | 1.03 (0.03) | AM – Placebo | 0.21 (0.04) | 0.0001 | (0.13 to 0.29) |
| PM | 1.04 (0.03) | PM – Placebo | 0.21 (0.04) | 0.0001 | (0.13 to 0.29) |
| Placebo | 0.82 (0.03) | AM – PM | −0.01 (0.04) | 0.8529 | (−0.09 to 0.07) |
| Steady state FEV1 | |||||
| AM | 1.11 (0.03) | AM – Placebo | 0.21 (0.04) | 0.0001 | (0.13 to 0.29) |
| PM | 1.06 (0.03) | PM – Placebo | 0.16 (0.04) | 0.0001 | (0.09 to 0.24) |
| Placebo | 0.90 (0.03) | AM – PM | 0.05 (0.04) | 0.2127 | (−0.03 to 0.12) |