Table 4

Strengths and limitations of the different definitions of ARDS

DefinitionStrengthsLimitations
Petty and Ashbaugh (1971)3• Detailed clinical description of the hallmarks of ARDS which remains relevant today• No formal criteria for identification of patients
Murray et al (1988)4• Three part definition evaluates chronicity, severity, and cause of lung injury• Lung injury score has not been predictive of mortality
• No formal criteria to exclude cardiogenic pulmonary oedema
North American-European Consensus Conference (1994)5• Simple criteria which are easy to apply in the clinical setting• Cause of lung injury not required
• Disease spectrum recognised by separation of ARDS from ALI• Radiographic criteria not sufficiently specific