Table 1

Individual and mean baseline characteristics and allergen challenge responses

Subject no	Age	M/F	Baseline FEV₁ (% pred)	Baseline MCh PC₂₀ (mg/ml)	Cumulative dose of allergen required to achieve initial EAR (SQ-U/ml)	Max fall in FEV₁ during EAR (% post saline)	Max fall in FEV₁ during LAR (% post saline)
*Geometric mean. †Fall in FEV₁ >15% on a single occasion, therefore not achieving criteria for an LAR.
Isolated early asthmatic responders (EAR)
1	35	M	89	0.39	29250	31.8	16.9†
2	29	M	114	5.43	29250	27.5	0.7
3	19	M	107	1.07	53250	49.7	12.2
4	24	F	111	7.41	74750	29.1	7.1
5	30	M	100	2.37	53250	37.6	8.3
6	23	M	96	0.08	750	21.8	0.0
7	25	F	95	0.30	21250	39.1	20.4†
8	33	M	97	0.57	13250	42.4	7.1
9	21	M	95	0.18	250	32.5	5.8
10	27	M	90	0.07	5250	36.4	5.5
Mean	27		99	0.61*	28050	34.8	8.4

Dual asthmatic responders (LAR)
1	24	F	104	0.14	2250	23.6	27.6
2	18	M	79	0.11	53250	38.1	24.8
3	24	M	83	0.34	1250	30.0	25.0
4	25	M	102	0.34	5250	24.4	65.8
5	21	M	99	0.70	13250	36.5	24.6
6	25	F	101	0.54	3250	34.0	19.6
7	24	F	70	0.37	3250	24.8	30.5
8	25	M	91	0.73	3250	40.8	38.8
9	25	M	73	0.36	750	20.0	28.1
10	24	M	111	0.84	3250	35.6	38.9
11	33	M	109	1.16	13250	49.0	46.9
12	27	F	90	1.99	1250	26.9	53.0
13	22	M	77	0.18	750	29.7	44.7
14	25	M	72	1.83	3250	20.0	16.5
15	25	M	92	0.09	3250	25.3	50.9
16	33	M	100	2.04	53250	42.2	70.0
17	24	F	88	0.08	5250	39.7	19.8
18	21	M	88	0.15	1250	26.1	16.0
19	23	M	85	0.27	750	26.7	48.7
20	22	F	97	0.12	7250	34.6	48.7
21	20	F	123	4.00	53250	27.2	31.7
Mean	24		92	0.42*	11036	31.2	36.7