Mean (SE) percentage collagen staining by area in the lamina propria of biopsy specimens from asthmatic and normal subjects with follow up data in the asthmatics following 3 and 12 months of treatment with inhaled fluticasone propionate (FP) or placebo (PL)
Controls (n=22) | Asthma (n=34) | PL +3 months (n=15) | FP +3 months (n=15) | PL +12 months (n=10) | FP +12 months (n=15) | |
---|---|---|---|---|---|---|
Collagen I | 53 (4) | 56 (4) | 56 (4) | 56 (4) | 48 (4) | 57 (4) |
Collagen III | 58 (4) | 54 (3) | 60 (3) | 57 (3) | 51 (4) | 59 (4) |