Table 2

Protective lung ventilation protocol from the ARDSNet study1

VariableSetting
Ventilator modeVolume assist-control
Tidal volume (initial) (ml/kg)6 (adjusted according to plateau pressure)
Plateau pressure (cm H2O)<30
Rate (breaths/min)6–35
I:E ratio1:1–1:3
Oxygenation target
    Pao2 (kPa)7.3–10.7
    Spo2 (%)88–95
PEEP and Fio2Set according to predetermined combinations (PEEP range 5–24 cm H2O)