Annual change in bone mineral density in 59 patients with cystic fibrosis aged ≥25 years
| Skeletal site | Baseline BMD* | Difference between baseline and follow up BMD* | Annual % change in BMD |
|---|---|---|---|
| Values are mean (95% CI). *BMD is measured in g/cm2 by DXA and SXA and in mg/ml by QCT. †p<0.05; ‡p=0.001; §p<0.001. | |||
| Lumbar spine (QCT) (n=44) | 170.8 (161.3 to 180.3) | 0.6 (−3.4 to 4.5) | 0.7 (−1.5 to 2.8) |
| Lumbar spine (DXA) (n=57) | 0.942 (0.909 to 0.975) | −0.001 (−0.011 to 0.010) | −0.0 (−1.3 to 1.2) |
| Femoral neck (DXA) (n=57) | 0.781 (0.746 to 0.816) | −0.015 (−0.022 to −0.007)§ | −1.9 (−2.9 to −0.8) |
| Total hip (DXA) (n=57) | 0.881 (0.844 to 0.918) | −0.013 (−0.020 to −0.006)‡ | −1.5 (−2.4 to −0.6) |
| Distal forearm (SXA) (n=56) | 0.515 (0.497 to 0.532) | −0.004 (−0.008 to −0.001)† | −0.8 (−1.5 to −0.1) |