Table 3

Mean (SE) changes in breathing pattern after placebo (saline), a single bronchodilator drug (either salbutamol or ipratropium but with data from both days combined, n=40)) and both drugs in combination

Baseline Change
after saline
Change after
single drug
Change after combination
Tidal volume (Vt) (l)0.69  (0.02)0.02  (0.02)0.09 (0.02)3-150 0.11  (0.02)3-150
Respiratory frequency (/min)24.4 (0.85)–0.13 (0.39)0.38 (0.51)0.98 (0.58)
Inspiratory time (Ti) (s)1.01 (0.04)–0.01 (0.02)0.02 (0.02)0.03 (0.03)
Total respiratory time (Ttot) (s)2.6 (0.09)0.02 (0.04)0.01 (0.05)–0.06 (0.07)
Ti/Ttot 0.39 (0.01)–0.01 (0)0.01 (0)0.41 (0.01)
Vt/Ti (l/s)0.71 (0.03)0.03 (0.01)0.09 (0.02)0.1 (0.03)
Vt/Te (l/s)0.46 (0.02)0.01 (0.01)0.07 (0.01)3-150 0.10 (0.01)3-150
  • 3-150 p<0.05.