Mean (SE) changes in breathing pattern after placebo (saline), a single bronchodilator drug (either salbutamol or ipratropium but with data from both days combined, n=40)) and both drugs in combination
Baseline |
Change after saline |
Change after single drug | Change after combination | |
Tidal volume (Vt) (l) | 0.69 (0.02) | 0.02 (0.02) | 0.09 (0.02)3-150 | 0.11 (0.02)3-150 |
Respiratory frequency (/min) | 24.4 (0.85) | –0.13 (0.39) | 0.38 (0.51) | 0.98 (0.58) |
Inspiratory time (Ti) (s) | 1.01 (0.04) | –0.01 (0.02) | 0.02 (0.02) | 0.03 (0.03) |
Total respiratory time (Ttot) (s) | 2.6 (0.09) | 0.02 (0.04) | 0.01 (0.05) | –0.06 (0.07) |
Ti/Ttot | 0.39 (0.01) | –0.01 (0) | 0.01 (0) | 0.41 (0.01) |
Vt/Ti (l/s) | 0.71 (0.03) | 0.03 (0.01) | 0.09 (0.02) | 0.1 (0.03) |
Vt/Te (l/s) | 0.46 (0.02) | 0.01 (0.01) | 0.07 (0.01)3-150 | 0.10 (0.01)3-150 |
↵3-150 p<0.05.