Table 2

Effect sizes for the relation of bronchial hyperresponsiveness (BHR) to serum total IgE, individual allergens, and lung function derived from a multiple regression analysis of a continuous measure compared with those expressed as odds ratios from the equivalent logistic regression model

Effect size derived from multiple regression*Effect size derived from odds ratio from logistic regression
FactorEffect size95% confidence intervalp valueEffect size95% confidence intervalp value
*Derived from the slope measure of BHR used in analyses of data from the European Community Respiratory Health Survey.18 Decreasing slope is increasing BHR, so here signs are reversed so that positive effect size represents increasing BHR with presence or increasing level of factor.
Total IgE (log kU/l)0.08–0.05 to–0.06 to 0.380.16
Specific IgE to:
    Cat0.340.05 to 0.630.020.550.11 to 1.000.02
    House dust mite (HDM) titre (just positive)0.420.22 to 0.62<0.0010.430.10 to 0.750.01
    per 10 kU/l increase in HDM titre above 0.35 kU/l0.130.03 to–0.06 to 0.240.22
    Timothy grass0.290.08 to 0.490.0050.640.33 to 0.95<0.001
    Cladosporium0.840.37 to 1.30<0.0011.200.49 to 1.910.001
    Birch–0.28–0.62 to 0.050.09–0.74–1.33 to –0.170.01
FEV1 as standardised difference from predicted value–0.22–0.31 to –0.12<0.001–0.35–0.52 to –0.18<0.001
FEV1 %FVC–0.05–0.07 to –0.04<0.001–0.06–0.08 to –0.03<0.001