Effect sizes for the relation of bronchial hyperresponsiveness (BHR) to serum total IgE, individual allergens, and lung function derived from a multiple regression analysis of a continuous measure compared with those expressed as odds ratios from the equivalent logistic regression model
| Effect size derived from multiple regression* | Effect size derived from odds ratio from logistic regression | |||||
|---|---|---|---|---|---|---|
| Factor | Effect size | 95% confidence interval | p value | Effect size | 95% confidence interval | p value |
| *Derived from the slope measure of BHR used in analyses of data from the European Community Respiratory Health Survey.18 Decreasing slope is increasing BHR, so here signs are reversed so that positive effect size represents increasing BHR with presence or increasing level of factor. | ||||||
| Total IgE (log kU/l) | 0.08 | –0.05 to 0.20 | 0.23 | 0.16 | –0.06 to 0.38 | 0.16 |
| Specific IgE to: | ||||||
| Cat | 0.34 | 0.05 to 0.63 | 0.02 | 0.55 | 0.11 to 1.00 | 0.02 |
| House dust mite (HDM) titre (just positive) | 0.42 | 0.22 to 0.62 | <0.001 | 0.43 | 0.10 to 0.75 | 0.01 |
| per 10 kU/l increase in HDM titre above 0.35 kU/l | 0.13 | 0.03 to 0.23 | 0.01 | 0.09 | –0.06 to 0.24 | 0.22 |
| Timothy grass | 0.29 | 0.08 to 0.49 | 0.005 | 0.64 | 0.33 to 0.95 | <0.001 |
| Cladosporium | 0.84 | 0.37 to 1.30 | <0.001 | 1.20 | 0.49 to 1.91 | 0.001 |
| Birch | –0.28 | –0.62 to 0.05 | 0.09 | –0.74 | –1.33 to –0.17 | 0.01 |
| FEV1 as standardised difference from predicted value | –0.22 | –0.31 to –0.12 | <0.001 | –0.35 | –0.52 to –0.18 | <0.001 |
| FEV1 %FVC | –0.05 | –0.07 to –0.04 | <0.001 | –0.06 | –0.08 to –0.03 | <0.001 |