Effect of Y-27632 on baseline lung resistance in OVA sensitised mice
| Group | Treatment (n) | Mean (95% CI) |
|---|---|---|
| Mice were separated into three groups (non-sensitised, OVA sensitised, and OVA sensitised RSV infected mice (OVA/RSV)) and treated with water or Y-27632 (30 mg/kg) 2 hours before measurement of baseline lung resistance. *p<0.05 v water gavage group. | ||
| Non-sensitised | Water (6) | 1.61 (1.57 to 1.65) |
| Y-27632 (6) | 1.61 (1.51 to 1.71) | |
| OVA sensitised | Water (8) | 1.58 (1.46 to 1.70) |
| Y-27632 (12) | 1.46 (1.40 to 1.52)* | |
| OVA/RSV | Water (7) | 2.28 (1.36 to 3.20) |
| Y-27632 (6) | 1.54 (1.42 to 1.67) | |