Variables at enrolment associated with failure of treatment
| Variable | Univariate analysis p value | Multivariate analysis | |||
|---|---|---|---|---|---|
| Odds ratio | p value | ||||
| Age | 0.569 | ||||
| Sex | 0.526 | ||||
| H+ | <0.001 | 1.22 (1.09 to 1.37) per nmol/l | <0.01 | ||
| Pao 2 | 0.035 | ||||
| Paco 2 | <0.001 | 1.14 (1.14 to 1.81) per kPa | <0.01 | ||
| Respiratory rate | 0.330 | ||||
| Radiographic consolidation | 0.136 | ||||
| Allocation to NIV | 0.038 | 0.39 (0.19 to 0.80) | <0.01 | ||
Paco2 , Pao 2 = arterial carbon dioxide and oxygen tensions; NIV = non-invasive ventilation.