Table 1

Characteristics of patients with acute exacerbations of chronic obstructive pulmonary disease assigned to standard treatment or non-invasive ventilation

Characteristic Standard treatment (n=118) NIV (n=118)
Mean (SD) age (years)69 (8)69 (7)
M:F63:5554:64
Respiratory rate (breaths/min)1-150 28 (24–40)28 (24–36)
pH1-150 7.31 (7.26–7.35)7.32 (7.25–7.35)
Mean (SD) Paco 2 (kPa)8.65 (1.70)8.82 (1.51)
Pao 2 (kPa)1-150 7.00 (4.71–12.31)6.88 (4.50–13.8)
FEV1 at discharge (l)1-150 0.68 (0.37–2.00)0.71 (0.28–1.47)
  • Paco2 , Pao 2 = arterial carbon dioxide and oxygen tensions; FEV1 = forced expiratory volume in one second.

  • 1-150 Median data with 5th and 95th centiles.