Odds ratios (95% CI) for eczema at 18–30 months associated with paracetamol and aspirin use (n=10216)
| No (eczema/total) | Unadjusted OR (95% CI) | Adjusted* OR (95% CI) | |
|---|---|---|---|
| *Adjusted for factors in table 1. | |||
| †Could not be estimated. | |||
| Paracetamol use in pregnancy: | |||
| 0–20 weeks | |||
| Never | 1202/4565 | 1.00 | 1.00 |
| Some days | 1389/5246 | 1.01 (0.92 to 1.10) | 0.99 (0.90 to 1.09) |
| Most days/daily | 31/128 | 0.89 (0.59 to 1.35) | 0.85 (0.56 to 1.30) |
| Unknown | 89/277 | 1.32 (1.02 to 1.72) | 1.51 (1.03 to 2.21) |
| 20–32 weeks | |||
| Never | 1416/5469 | 1.00 | 1.00 |
| Some days | 1083/4022 | 1.05 (0.96 to 1.16) | 1.04 (0.94 to 1.14) |
| Most days/daily | 25/96 | 1.01 (0.64 to 1.60) | 1.04 (0.65 to 1.66) |
| Unknown | 187/629 | 1.21 (1.01 to 1.45) | 1.13 (0.62 to 2.07) |
| Aspirin use in pregnancy: | |||
| 0–20 weeks | |||
| Never | 2483/9472 | 1.00 | 1.00 |
| Some days | 122/416 | 1.17 (0.94 to 1.45) | 1.23 (0.99 to 1.53) |
| Most days/daily | 24/69 | 1.50 (0.91 to 2.47) | 1.42 (0.84 to 2.39) |
| Unknown | 82/259 | 1.30 (1.00 to 1.70) | 1.52 (1.01 to 2.29) |
| 20–32 weeks | |||
| Never | 2432/9270 | 1.00 | 1.00 |
| Some days | 71/253 | 1.10 (0.83 to 1.45) | 1.14 (0.85 to 1.51) |
| Most days/daily | 21/64 | 1.37 (0.81 to 2.32) | 1.27 (0.73 to 2.20) |
| Unknown | 187/629 | 1.19 (1.00 to 1.42) | 1.12 (0.61 to 2.04) |
| Paracetamol use in infancy: | |||
| 0–6 months | |||
| Never | 285/1279 | 1.00 | 1.00 |
| Once | 496/1916 | 1.22 (1.03 to 1.44) | 1.17 (0.99 to 1.38) |
| More than once | 1771/6416 | 1.33 (1.15 to 1.53) | 1.22 (1.05 to1.41) |
| Unknown | 159/605 | 1.24 (0.99 to 1.56) | –† |