Table 2

Mutually adjusted effects of childhood exposures on symptoms in subjects aged 20–44 years

VariableWheeze*Wheeze + SOB†Wheeze – cold‡Waking with SOB§Hay fever¶Eczema**
Values are odds ratios (95% CI) estimated by logistic regression adjusted for age, sex, parental smoking, current smoking, current occupation, and study centre.
SOB = shortness of breath.
*“Have you had wheezing or whistling in your chest at any time in the last 12 months?”
†“(If yes) have you been at all breathless when the wheezing was present?”
‡“(If yes) have you had this wheezing or whistling when you did not have a cold?”
§“Have you been woken by an attack of shortness of breath at any time in the last 12 months?”
¶“Do you have any nasal allergies, including hay fever?”
**“Have you ever had eczema or any kind of skin allergy?”
Family size
    0 sibs111111
    1 sib0.95 (0.83 to 1.09)0.98 (0.82 to 1.18)1.00 (0.83 to 1.18)1.00 (0.79 to 1.28)0.94 (0.83 to 1.06)0.94 (0.84 to 1.06)
    2 sibs0.90 (0.78 to 1.04)0.92 (0.76 to 1.11)0.91 (0.76 to 1.08)0.97 (0.75 to 1.25)0.84 (0.74 to 0.96)0.93 (0.82 to 1.05)
    3 sibs0.96 (0.82 to 1.13)1.13 (0.92 to 1.38)1.04 (0.86 to 1.27)1.16 (0.88 to 1.52)0.78 (0.67 to 0.90)0.91 (0.79 to 1.04)
    ≥4 sibs1.04 (0.89 to 1.21)1.17 (0.95 to 1.43)1.09 (0.90 to 1.32)1.22 (0.94 to 1.60)0.74 (0.64 to 0.85)0.85 (0.75 to 0.97)
Bedroom sharing
    No111111
    Yes1.05 (0.97 to 1.14)1.02 (0.92 to 1.13)1.03 (0.93 to 1.13)0.97 (0.85 to 1.12)0.97 (0.90 to 1.05)0.98 (0.91 to 1.05)
Day care attendance
    No111111
    Yes1.01 (0.93 to 1.10)1.04 (0.94 to 1.16)0.96 (0.87 to 1.07)1.02 (0.89 to 1.18)1.01 (0.94 to 1.10)1.04 (0.97 to 1.12)
Serious respiratory infection
    No111111
    Yes1.86 (1.66 to 2.09)2.06 (1.80 to 2.37)1.70 (1.49 to 1.95)1.85 (1.54 to 2.22)1.44 (1.29 to 1.61)1.34 (1.20 to 1.49)