Isoniazid and multidrug resistance by year of diagnosis, country of diagnosis, diagnosis in London, history of previous treatment, and HIV infection status, 1993–9, UK
| Isoniazid resistance* | Multidrug resistance | ||||
|---|---|---|---|---|---|
| All isolates | No (%) | 95% CI | No (%) | 95% CI | |
| *Isoniazid resistance: with or without resistance to other drugs. | |||||
| Year | |||||
| 1993 | 3409 | 157 (4.6) | (3.9 to 5.4) | 19 (0.6) | (0.3 to 0.9) |
| 1994 | 3253 | 181 (5.6) | (4.8 to 6.4) | 43 (1.3) | (1.0 to 1.8) |
| 1995 | 3253 | 197 (6.1) | (5.3 to 6.9) | 49 (1.5) | (1.1 to 2.0) |
| 1996 | 3632 | 221 (6.1) | (5.3 to 6.9) | 60 (1.7) | (1.3 to 2.1) |
| 1997 | 3578 | 193 (5.3) | (4.7 to 6.2) | 45 (1.3) | (0.9 to 1.7) |
| 1998 | 3832 | 230 (6) | (5.3 to 6.8) | 50 (1.3) | (1.0 to 1.7) |
| 1999 | 4260 | 253 (5.9) | (5.2 to 6.7) | 33 (0.8) | (0.5 to 1.1) |
| Total | 25217 | 1432 (5.7) | (5.4 to 6.0) | 299 (1.2) | (1.1 to 1.3) |
| Country in which diagnosed | |||||
| England | 21913 | 1307 (6.0) | (5.7 to 6.3) | 277 (1.3) | (1.1 to 1.4) |
| N Ireland | 354 | 11 (3.1) | (1.6 to 5.5) | 1 (0.3) | (0.0 to 1.6) |
| Scotland | 2148 | 78 (3.6) | (2.9 to 4.5) | 15 (0.7) | (0.4 to 1.1) |
| Wales | 788 | 35 (4.4) | (3.1 to 6.1) | 5 (0.6) | (0.2 to 1.5) |
| Place of diagnosis | |||||
| London | 9275 | 701 (7.6) | (7.0 to 8.1) | 157 (1.7) | (1.4 to 2.0) |
| Outside London | 15932 | 730 (4.6) | (4.3 to 4.9) | 142 (0.9) | (0.8 to 1.0) |
| History of TB | |||||
| Previous | 1396 | 217 (15.5) | (13.7 to 17.6) | 131 (9.4) | (7.9 to 11.0) |
| No previous TB | 6207 | 352 (5.7) | (5.1 to 6.3) | 49 (0.8) | (0.6 to 1.0) |
| Unknown | 17614 | 863 (4.9) | (4.6 to 5.2) | 119 (0.7) | (0.6 to 0.8) |
| HIV infection | |||||
| Positive | 910 | 106 (11.6) | (9.6 to 13.9) | 42 (4.6) | (3.3 to 6.2) |
| Negative or unknown | 24307 | 1324 (5.4) | (5.2 to 5.7) | 257 (1.1) | (0.9 to 1.2) |