Resistance to first line drugs in Mycobacterium tuberculosis isolates 1993–9, UK
M tuberculosis | M africanum | M bovis | Total | |
---|---|---|---|---|
*Monoresistance: resistance to only one drug. | ||||
†Any resistance: resistance to stated drug with or without resistance to other drugs. | ||||
‡MDR-TB: multidrug resistance (resistance to at least isoniazid and rifampicin). | ||||
Number of isolates | 24876 | 50 | 291 | 25217 |
Resistance to any drug | 1523 (6.1%) | 4 (8%) | 34 (11.7%) | 1559 (6.2%) |
Monoresistance* | 1269 (5.1%) | 3 (6%) | 29 (10%) | 1301 (5.2%) |
Isoniazid: any resistance† | 1397 (5.6%) | 1 (2.0%) | 34 (11.7%) | 1432 (5.7%) |
Rifampicin: any resistance† | 332 (1.3%) | 2 (4%) | 6 (2.1%) | 340 (1.3%) |
Ethambutol any resistance† | 148 (0.6%) | 1 (2.0%) | 0 | 149 (0.6%) |
Pyrazinamide: any resistance† | 173/20899 (0.8%) | 1/48 (2.1%) | – | 174 (0.8%) |
Streptomycin: any resistance† | 767/12950 (5.9%) | 2/43 (4.7%) | 2/140 (1.4%) | 771 (5.9%) |
MDR-TB‡ | 292 (1.2%) | 1 (2.0%) | 6 (2.1%) | 299 (1.2%) |