Table 1

Resistance to first line drugs in Mycobacterium tuberculosis isolates 1993–9, UK

M tuberculosisM africanumM bovisTotal
*Monoresistance: resistance to only one drug.
†Any resistance: resistance to stated drug with or without resistance to other drugs.
‡MDR-TB: multidrug resistance (resistance to at least isoniazid and rifampicin).
Number of isolates248765029125217
Resistance to any drug1523 (6.1%)4 (8%)34 (11.7%)1559 (6.2%)
Monoresistance*1269 (5.1%)3 (6%)29 (10%)1301 (5.2%)
Isoniazid: any resistance†1397 (5.6%)1 (2.0%)34 (11.7%)1432 (5.7%)
Rifampicin: any resistance†332 (1.3%)2 (4%)6 (2.1%)340 (1.3%)
Ethambutol any resistance†148 (0.6%)1 (2.0%)0149 (0.6%)
Pyrazinamide: any resistance†173/20899 (0.8%)1/48 (2.1%)174 (0.8%)
Streptomycin: any resistance†767/12950 (5.9%)2/43 (4.7%)2/140 (1.4%)771 (5.9%)
MDR-TB‡292 (1.2%)1 (2.0%)6 (2.1%)299 (1.2%)