Table 1

Clinical information on HLA-DRB1*0301+, DRB1*0301–/DRB3*0101–, and DRB1*0301–/DRB3*0101+ sarcoidosis patients

DRB1*0301+ (n=69)DRB1*0301–/ DRB3*0101– (n=46)DRB1*0301–/ DRB3*0101+ (n=6)
All figures (except age) are numbers (%) of patients. †Smoking cessation >5 years ago; ‡at the time of bronchoscopy; §one patient on inhaled treatment; ¶one patient on oral and three on inhaled treatment.
Median (min–max) age (years) 36 (24–62) 40 (25–66)34 (24–36)
Sex male/female 45/24 (65/32) 25/21 (54/46)3/3 (40/60)
Smoking habits
    Yes 6 (9) 6 (13)0
    Ex-smoker†12 (17) 9 (20)3 (50)
    Never smoker51 (74)31 (67)3 (50)
Chest radiographic staging:
    Stage 0 4 (6) 00
    Stage I45 (65)15 (33)3 (50)
    Stage II18 (26)25 (54)2 (33)
    Stage III 2 (3) 6 (13)1 (17)
Treatment‡
    Not treated54 (78)39 (85)4 (67)
    Treatment with NSAID14 (20) 3 (7)2 (33)
    Treatment with steroids 1 (1)§ 4 (9)¶0
Pulmonary sarcoidosis66 (96)46 (100)6 (100)
Löfgren's syndrome49 (75) 6 (13)4 (67)