Initial and annual change in lung function in patients with infrequent and frequent exacerbations
| Starting value | Annual change | |||
|---|---|---|---|---|
| Infrequent | Frequent | Infrequent | Frequent | |
| PEF=peak expiratory flow; FEV1=forced expiratory volume in 1 second. | ||||
| *p<0.05, ***p<0.001 annual rates of change between infrequent and frequent exacerbators. | ||||
| Exacerbations (reported and unreported) | <50% percentile, <2.92 per year | > 50% percentile >2.92 per year | ||
| (n=63) | (n=46) | |||
| PEF (l/min) | 214 | 232 | –0.72 | –2.94*** |
| (n=16) | (n=16) | |||
| FEV1 (ml) | 893 | 950 | –32.1 | –40.1* |