Comparison of mean healthcare use between the treatments. Each value represents the mean resource use per patient over each treatment period
| Daily rhDNase v hypertonic saline | Daily rhDNase v alternate day rhDNase | |||||
|---|---|---|---|---|---|---|
| Daily (n=40) | Saline (n=40) | Mean difference (95% CI) | Daily (n=43) | Alternate (n=43) | Mean difference (95% CI) | |
| Hospital resource use | ||||||
| Hospital admissions | 0.63 | 0.53 | 0.10 (−0.15 to 0.35) | 0.63 | 0.79 | −0.16 (−0.41 to 0.09) |
| Inpatient days (total) | 4.73 | 5.13 | −0.40 (−2.32 to 1.52) | 4.47 | 5.40 | −0.93 (−3.24 to 1.38) |
| Due to pulmonary exacerbation | 2.33 | 4.28 | −1.95 (−4.22 to 0.32) | 2.21 | 2.91 | −0.70 (−2.74 to 1.34) |
| Outpatient visits | 0.93 | 1.23 | −0.30 (−0.71 to 0.11) | 1.00 | 0.86 | 0.14 (−0.28 to 0.56) |
| Day case visits | 0.33 | 0.35 | −0.03 (−0.30 to 0.25) | 0.37 | 0.40 | −0.02 (−0.31 to 0.27) |
| Days of IV antibiotic therapy | 9.45 | 10.38 | −0.93 (−4.45 to 2.60) | 9.56 | 8.84 | 0.72 (−2.36 to 3.81) |
| Community service use | ||||||
| GP contacts | 0.30 | 0.25 | 0.05 (−0.17 to 0.27) | 0.28 | 0.21 | 0.07 (−0.14 to 0.28) |
| Nurse contacts | 1.75 | 2.70 | −0.95 (−0.17 to 0.25) | 1.70 | 2.26 | −0.56 (−3.43 to 2.32) |
| Physiotherapist contacts | 0.33 | 0.10 | 0.23 (−0.09 to 0.54) | 0.30 | 0.12 | 0.19 (−0.02 to 0.39) |