Baseline characteristics of the study population (n=47)
| Mean (SD) | Range | |
|---|---|---|
| FEV1=forced expiratory volume in 1 second; FVC=forced vital capacity. | ||
| *Scores fall between the limits of 0 and 1, with higher scores indicating greater well being. | ||
| †Number of children with three positive cultures of the following organisms in the past year. | ||
| Age (years) | 12.6 (2.8) | 7.3–17.0 |
| FEV1 (litres) | 1.18 (0.47) | 0.44–2.34 |
| FEV1 (% predicted) | 48 (15) | 14–77 |
| FVC (% predicted) | 68 (22) | 20–112 |
| Quality of Well-Being Scale* | 0.61 (0.12) | 0.35–0.84 |
| n (%) | ||
| Females | 28 (60%) | |
| Treatment at enrolment | ||
| Hypertonic saline | 2 (4%) | |
| rhDNase | 39 (83%) | |
| Lung microbiology† | ||
| Pseudomonas aeruginosa | 17 (36%) | |
| Staphylococcus aureus | 13 (28%) | |
| Both organisms | 5 (11%) | |