Table 1

Baseline characteristics of the study population (n=47)

Mean (SD)Range
FEV1=forced expiratory volume in 1 second; FVC=forced vital capacity.
*Scores fall between the limits of 0 and 1, with higher scores indicating greater well being.
†Number of children with three positive cultures of the following organisms in the past year.
Age (years)12.6 (2.8)7.3–17.0
FEV1 (litres)1.18 (0.47)0.44–2.34
FEV1 (% predicted)48 (15)14–77
FVC (% predicted)68 (22)20–112
Quality of Well-Being Scale*0.61 (0.12)0.35–0.84
n (%)
Females28 (60%)
Treatment at enrolment
    Hypertonic saline2 (4%)
    rhDNase39 (83%)
Lung microbiology†
    Pseudomonas aeruginosa17 (36%)
    Staphylococcus aureus13 (28%)
    Both organisms5 (11%)