Table 2

Peak cough expiratory flow rate (PCEF), cough expiratory volume (CEV), and peak value time (PVT) in subjects during the various assisted cough techniques

Normal subjects (n=9)COPD (n=8)Neuromuscular weakness
Without scoliosis (n=8)With scoliosis (n=4)
Baseline
 PCEF (l/min)668 (310–700)370 (267–483)104 (43–188)288 (175–367)
 CEV (l)2.4 (1.31–4.91)1.02 (0.4–2.51)0.5 (0.3–0.8)0.9 (0.50–1.1)
 PVT (ms)35 (30–45)32 (25–40)80 (40–220)44 (40–50)
Manually assisted cough
 PCEF (l/min)624 (326–700)226 (120–315)2-150 185 (93–355)2-150 193 (185–287)
 CEV (l)2.91 (1.31–5.31)0.8 (0.20–1.51)0.7 (0.31–1.07)0.5 (0.41–1.01)
 PVT (ms)50 (40–85)** 45 (30–60)2-150 118 (35–360)2-150 50 (35–55)
Mechanical insufflation
 PCEF (l/min)676 (494–695)288 (218–370)156 (61–247)231 (148–597)
 CEV (l)2.2 (0.8–5.91)0.45 (0.2–0.91)2-150 0.6 (0.3–1.61)0.7 (0.3–1.3)
 PVT (ms)35 (30–40)33 (30–40)85 (20–420)45 (30–60)
In combination
 PCEF (l/min)624 (288–695)245 (218–370)2-150 248 (110–343)2-150 362 (218–440)
 CEV (l)2.2 (0.7–5.41)0.8 (0.3–1.00)0.6 (0.40–2.19)0.6 (0.4–1.01)
 PVT (ms)55 (40–100)40 (35–50)75 (20–420)50 (45–120)
  • Data are expressed as median (range).

  • 2-150 p<0.01.