Association of maximum % fall in FEV1 after exercise with respiratory symptoms and asthma
| Children without symptoms | Children with symptoms | ||||||
|---|---|---|---|---|---|---|---|
| N | Mean % reduction (95% CI) | N | Mean % reduction (95% CI) | Difference in means (95% CI) | p Value | ||
| At any time: | |||||||
| Asthma | 697 | 9.5 (8.7 to 10.2) | 75 | 12.1 (9.4 to 14.8) | –2.6 (–5.1 to –0.1) | 0.038 | |
| Bronchospasm | 641 | 9.5 (8.7 to 10.2) | 131 | 11.0 (9.0 to 13.0) | –1.6 (–3.5 to 0.4) | 0.112 | |
| Bronchodilator therapy3-151 | 612 | 9.3 (8.5 to 10.1) | 133 | 11.4 (9.3 to 13.5) | –2.0 (–4.0 to –0.1) | 0.038 | |
| Asthma to bronchospasm or bronchodilator therapy | 618 | 9.2 (8.5 to 10.0) | 154 | 11.7 (9.7 to 13.6) | –2.5 (–4.2 to –0.6) | 0.010 | |
| In the last 12 months (numbers refer to question numbers in table 1): | |||||||
| (1) Wheeze3-152 | 701 | 9.5 (8.7 to10.2) | 70 | 12.0 (9.4 to14.5) | –2.5 (–5.0 to 0.0) | 0.054 | |
| (2) Chest tightness | 704 | 9.0 (8.3 to 9.8) | 68 | 17.0 (14.0 to 19.9) | –7.9 (–10.5 to–5.4) | <0.001 | |
| (3) Agitated breathing | 692 | 9.4 (8.6 to 10.1) | 80 | 12.8 (10.5 to 15.1) | –3.4 (–5.8 to –1.0) | 0.005 | |
| (4) Waking with tight chest | 748 | 9.7 (8.9 to 10.4) | 24 | 11.2 (7.6 to 14.8) | –1.5 (–5.8 to 2.7) | 0.471 | |
| (5) Shortness of breath | 709 | 9.4 (8.7 to 10.2) | 63 | 13.2 (10.0 to 16.4) | –3.8 (–6.4 to –1.1) | 0.005 | |
| (6) Waking with shortness of breath | 732 | 9.6 (8.9 to 10.3) | 40 | 11.8 (7.7 to 16.0) | –2.2 (–5.5 to 1.1) | 0.188 | |
| (7) Waking with cough3-152 | 505 | 9.6 (8.7 to 10.5) | 267 | 9.9 (8.8 to 11.1) | –0.3 (–1.9 to 1.2) | 0.660 | |
| (8) Asthma attack | 746 | 9.6 (8.9 to10.4) | 26 | 12.7 (8.6 to16.8) | –3.1 (–7.1 to 1.0) | 0.136 | |
| Any respiratory symptom of asthma3-150 | 603 | 8.6 (7.8 to 9.4) | 169 | 13.7 (11.9 to15.5) | –5.1 (–6.8 to –3.4) | <0.001 | |