Table 2

Association of pre-exercise % predicted FEV1 with respiratory symptoms and asthma

Children without symptomsChildren with symptoms
NMean % of predicted value (95% CI)NMean % of predicted value (95% CI)Difference in means (95% CI)p Value
At any time:
 Asthma714104.4 (103.3 to 105.6)79100.1 (96.7 to 103.6)4.3 (0.7 to 8.0)0.019
 Bronchospasm653104.6 (103.5 to 105.8)140101.1 (98.0 to 104.2)3.5 (0.7 to 6.4)0.015
 Bronchodilator therapy2-151 623104.8 (103.6 to 105.9)141101.0 (98.2 to 103.7)3.8 (1.0 to 6.6)0.007
 Asthma to bronchospasm or bronchodilator therapy629104.7 (103.6 to 105.9)164101.4 (98.5 to 104.2)3.4 (0.7 to 6.0)0.014
In the last 12 months (numbers refer to question numbers in table 1):
 (1) Wheeze2-152 717104.4 (103.3 to 105.5)75100.3 (96.2 to 104.3)4.1 ( 0.4 to 7.8)0.029
 (2) Chest tightness719104.5 (103.4 to 105.6)74 99.5 (94.7 to 104.3)4.9 (1.2 to 8.7)0.009
 (3) Agitated breathing704104.8 (103.7 to 105.9)89 97.8 (93.4 to 102.1)7.1 (3.6 to 10.5)<0.001
 (4) Waking with tight chest766104.2 (103.2 to 105.3)27 97.4 (89.8 to 105.1)6.8 (0.8 to 12.8)0.026
 (5) Shortness of breath722104.6 (103.5 to 105.7)71 97.8 (92.9 to 102.6)6.9 (3.1 to 10.6)<0.001
 (6) Waking with shortness of breath748104.4 (103.3 to 105.5)45 97.9 (91.8 to 104.0)6.5 (1.8 to 11.2)0.007
 (7) Waking with cough2-152 516104.0 (102.7 to 105.3)276104.2 (102.2 to 106.1)–0.1 (–2.4 to 2.1)0.915
 (8) Asthma attack763104.3 (103.2 to 105.4)30 96.2 (88.2 to 104.3)8.1 (2.4 to 13.8)0.005
 Any respiratory symptom of asthma2-150 609105.3 (104.1 to 106.4)184 99.9 (97.1 to 102.7)5.3 (2.8 to 7.9)<0.001
  • 2-150 Any of symptoms listed in questions 1 to 6 (see table 1) during the last 12 months.

  • 2-151 Information not available for 29 children.

  • 2-152 Information not available for one child.