Table 2

Calculation of diagnostic statistics using diagnosed asthma as the index of “disease present or absent” and airway hyperresponsiveness as the index of “test positive or negative”

Disease present (diagnosed asthma) Disease absent Total
Test positive (AHR)358  (a)220  (b)578
Test negative 557 (c)1919 (d)2476
Total91521393054
  • Sensitivity = a/(a+c) = 0.39; specificity = d/(b+d) = 0.90; positive predictive value = a/(a+b) = 0.62; negative predictive value = d/(c+d) = 0.78; positive likelihood ratio = sensitivity/ (1—specificity) = 3.9.