Table 2

Pre-bronchodilator spirometric data for 108 patients separated by degree of impairment of FEV1

Impairment of FEV1
None (n=32)Mild (n=19)Moderate (n=36)Severe (n=21)
FEV1(l)2.31  (0.61)1.77  (0.44)2-160 1.27  (0.32)2-165 0.74  (0.19)2-165
FEV1 (% predicted)94.7 (11.0)69.6 (6.2)51.4 (5.6)29.3 (7.0)
FVC (l)3.3 (0.8)2.9 (0.6)2.8 (0.9)2.25 (0.8)2-170
FVC (% predicted)108.5 (12.7)93.1 (15.1)2-160 87.4 (15.9)67.0 (17.2)2-165
VC (l)3.38 (0.88)2.99 (0.61)2.97 (0.9)2.47 (0.75)2-164
VC (% predicted)110.9 (13.3)96.0 (15.2)2-160 93.8 (16.9)73.6 (15.8)2-165
FEV1/FVC (%)70.6 (9.2)61.1 (10.4)47.2 (9.6)2-160 34.0 (7.3)2-150
FEV1/VC (%)69.2 (9.8)59.2 (10.2)44.4 (9.3)2-160 30.6 (5.9)2-150
  • FEV1 = forced expiratory volume in one second; FVC = forced vital capacity; VC = relaxed vital capacity; FEV1/(F)VC% = FEV1/(F)VC ratio expressed as a percentage.

  • Data are means (SD).

  • 2-150 p<0.05;

  • 2-160 p<0.01;

  • 2-165 p<0.001 compared with the adjacent less severe category of FEV1 impairment (one way ANOVA with post-hoc comparison).

  • 2-164 p<0.01 severe versus no impairment;

  • 2-170 p<0.001 severe versus no impairment.