Factor | Unadjusted hazard of death (95% CI) | p value5-152 | Adjusted hazard of death (95% CI) | p value5-154 |
Age group (years) | <0.0001 | <0.0001 | ||
<60 | 1.0 | 1.0 | ||
60–69 | 1.15 (1.04 to 1.28) | 1.10 (0.99 to 1.22) | ||
70–79 | 1.53 (1.38 to 1.69) | 1.34 (1.21 to 1.49) | ||
80+ | 2.23 (1.97 to 2.51) | 1.42 (1.24 to 1.63) | ||
Sex | 0.28 | 0.0001 | ||
Male | 1.0 | 1.0 | ||
Female | 0.96 (0.90 to 1.03) | 0.88 (0.82 to 0.94) | ||
Deprivation quintile | 0.0033 | 0.0033 | ||
1 (least deprived) | 1.0 | 1.0 | ||
2 | 0.99 (0.88 to 1.11) | 1.05 (0.93 to 1.19) | ||
3 | 1.03 (0.92 to 1.16) | 1.11 (0.99 to 1.24) | ||
4 | 1.06 (0.94 to 1.18) | 1.12 (1.00 to 1.25) | ||
5 (most deprived) | 1.18 (1.06 to 1.31) | 1.22 (1.10 to 1.36) | ||
Clinical extent of disease | <0.0001 | <0.0001 | ||
Localised | 1.0 | 1.0 | ||
Regional spread | 1.64 (1.51 to 1.80) | 1.61 (1.47 to 1.75) | ||
Distant spread | 3.09 (2.83 to 3.37) | 2.81 (2.57 to 3.07) | ||
Not known | 2.85 (2.54 to 3.19) | 1.80 (1.59 to 2.03) | ||
Histology | <0.0001 | <0.0001 | ||
NSCLC5-160 | 1.0 | 1.0 | ||
SCLC | 1.37 (1.25 to 1.50) | 1.27 (1.16 to 1.40) | ||
Not known5-164 | 1.90 (1.76 to 2.05) | 1.05 (0.96 to 1.14) | ||
Diagnosis by or referral to specialist within 6 months | <0.0001 | <0.0001 | ||
Yes | 1.0 | 1.0 | ||
No | 3.71 (3.36 to 4.10) | 1.95 (1.75 to 2.18) | ||
Active treatment within 6 months | <0.0001 | <0.0001 | ||
Yes | 1.0 | 1.0 | ||
No | 2.69 (2.51 to 2.88) | 2.04 (1.88 to 2.21) | ||
Potentially curative treatment within 6 months | <0.0001 | Not applicable5-161 | ||
Yes | 1.0 | |||
No | 3.31 (2.99 to 3.66) | |||
Surgical resection within 6 months | <0.0001 | Not applicable5-161 | ||
Yes | 1.0 | |||
No | 4.47 (3.92 to 5.10) |
↵5-150 Derived from univariate Cox's proportional hazards model.
↵5-151 Derived from a multivariate Cox's proportional hazards model.
↵5-152 p values for the factors are the Wald statistics for the estimates in the model, conditional on the other factors being present.
↵5-154 p values for the factors are the Wald statistics for the estimates in the model, conditional on the other factors being present.
↵5-160 Includes cases with a recorded histological type known not to be small cell lung cancer (SCLC).
↵5-164 Includes cases with type not known or not recorded and those with no microscopic verification.
↵5-161 Neither the potentially curative treatment nor surgical resection factors were offered to the multivariate Cox model.