Table 5

Unadjusted5-150 and adjusted5-151 hazard ratios of death with a minimum of 3 years follow up, based on all cases (n=3855)

Factor Unadjusted hazard of death (95% CI) p value5-152 Adjusted hazard of death (95% CI) p value5-154
Age group (years)<0.0001<0.0001
 <601.01.0
 60–691.15 (1.04 to 1.28)1.10 (0.99 to 1.22)
 70–791.53 (1.38 to 1.69)1.34 (1.21 to 1.49)
 80+2.23 (1.97 to 2.51)1.42 (1.24 to 1.63)
Sex 0.280.0001
 Male1.01.0
 Female0.96 (0.90 to 1.03)0.88 (0.82 to 0.94)
Deprivation quintile0.00330.0033
 1 (least deprived)1.01.0
 20.99 (0.88 to 1.11)1.05 (0.93 to 1.19)
 31.03 (0.92 to 1.16)1.11 (0.99 to 1.24)
 41.06 (0.94 to 1.18)1.12 (1.00 to 1.25)
 5 (most deprived)1.18 (1.06 to 1.31)1.22 (1.10 to 1.36)
Clinical extent of disease <0.0001<0.0001
 Localised1.01.0
 Regional spread1.64 (1.51 to 1.80)1.61 (1.47 to 1.75)
 Distant spread3.09 (2.83 to 3.37)2.81 (2.57 to 3.07)
 Not known2.85 (2.54 to 3.19)1.80 (1.59 to 2.03)
Histology<0.0001<0.0001
 NSCLC5-160 1.01.0
 SCLC1.37 (1.25 to 1.50)1.27 (1.16 to 1.40)
 Not known5-164 1.90 (1.76 to 2.05)1.05 (0.96 to 1.14)
Diagnosis by or referral to specialist within 6 months<0.0001<0.0001
 Yes1.01.0
 No3.71 (3.36 to 4.10)1.95 (1.75 to 2.18)
Active treatment within 6 months<0.0001<0.0001
 Yes1.01.0
 No2.69 (2.51 to 2.88)2.04 (1.88 to 2.21)
Potentially curative treatment within 6 months<0.0001Not applicable5-161
 Yes1.0
 No3.31 (2.99 to 3.66)
Surgical resection within 6 months<0.0001Not applicable5-161
 Yes1.0
 No4.47 (3.92 to 5.10)
  • 5-150 Derived from univariate Cox's proportional hazards model.

  • 5-151 Derived from a multivariate Cox's proportional hazards model.

  • 5-152 p values for the factors are the Wald statistics for the estimates in the model, conditional on the other factors being present.

  • 5-154 p values for the factors are the Wald statistics for the estimates in the model, conditional on the other factors being present.

  • 5-160 Includes cases with a recorded histological type known not to be small cell lung cancer (SCLC).

  • 5-164 Includes cases with type not known or not recorded and those with no microscopic verification.

  • 5-161 Neither the potentially curative treatment nor surgical resection factors were offered to the multivariate Cox model.