Table 3

Mean (SE) cytokine expression in peripheral and alveolar memory and naive lymphocytes from all sarcoidosis patients

IFNγIL-2TNFαIL-4IL-5IL-10
Blood
 Naive7.8  (2.3)6.9  (2.7)4.5  (1.5)0.9  (0.2)0.3  (0.1)0.9  (0.2)
 Memory10.4 (1.9)13.4 (3.2)15.8 (4.2)3-150 5.2 (1.0)3-150 2.7 (1.0)3-150 3.4 (1.0)3-150
BAL fluid
 Naive17.5 (5.9)6.8 (3.2)13.4 (5.5)1.0 (0.4)0.2 (1.0)2.5 (0.7)
 Memory27.2 (5.9)3-160 18.4 (6.4)26.7 (7.5)0.9 (0.2)3-160 0.6 (1.0)1.6 (0.4)

  • IFNγ = interferon gamma; IL = interleukin; TNFα = tumour necrosis factor alpha.

  • ↵3-150 p<0.05 compared with peripheral naive lymphocytes.

  • ↵3-160 p<0.05 compared with peripheral memory lymphocytes.