Frequencies of the−15Thr→Ala signal peptide genotypes in healthy controls and in CF patients with and without plasma α1-antichymotrypsin (ACT) deficiency
| ACT genotype | CF + deficient ACT (n=10) | CF + normal ACT (n=42) | Controls (n=45) |
| AA (GG) (%) | 6 (60%) | 20 (47.6%) | 11 (24.4%) |
| AT (GA) (%) | 2 (20%) | 15 (35.7%) | 26 (57.8%) |
| TT (AA) (%) | 2 (20%) | 7 (16.7%) | 8 (17.8%) |
| ACT A (G) allele | 0.7 | 0.65 | 0.53 |
| ACT T (A) allele | 0.3 | 0.35 | 0.47 |