Table 1

Clinical characteristics of children with difficult asthma

Number23
Age (years) 11.7 (10.4 to 13.1)
Male:female13:10
Inhaled steroid dose (μg/day)
 Budesonide (n=9) 2144 (1701 to 2588)
 Fluticasone (n=14)1500 (1216 to 1927)
Maintenance oral prednisolone6
Long acting bronchodilator17
Baseline FEV1 (% pred) 72 (63 to 81)
Post-bronchodilator FEV1 (% pred)82 (74 to 90)
Alternative treatments8 (theophylline n=4; theophylline and subcutaneous terbutaline n=1; cyclosporin n=1; monteleukast n=2)
Atopic23
  • FEV1 = forced expiratory volume in one second.

  • Data are expressed as means with 95% confidence intervals, or proportions.