Table 2

Adjusted odds ratio for symptoms and airway hyperresponsiveness (AHR) in atopic and non-atopic subjects compared with a group of normal weight

Underweight
(BMI <18.5)
Overweight
(BMI 25–29.9)
Moderate obesity
(BMI 30–34.9)
Severe obesity
(BMI ⩾35.0)
Wheeze in last 12 months
 Atopics1.75 (0.80 to 3.82)0.97 (0.68 to 1.38)1.24 (0.70 to 2.20)1.71 (0.73 to 4.02)
 Non-atopics0.57 (0.16 to 2.05)1.31 (0.86 to 2.00)2.37 (1.23 to 4.56)5.10 (2.27 to 11.45)
Recent asthma
 Atopics1.42 (0.59 to 3.45)0.99 (0.65 to 1.51)1.21 (0.62 to 2.35)1.43 (0.54 to 3.79)
 Non-atopics0.38 (0.05 to 3.02)0.90 (0.47 to 1.72)2.21 (0.92 to 5.33)4.08 (1.52 to 10.98)
SOBOE
 Atopics2.34 (0.71 to 7.76)1.18 (0.76 to 1.84)1.89 (0.98 to 3.64)2.96 (1.15 to 7.62)
 Non-atopics2.99 (0.86 to 10.31)1.92 (1.23 to 2.97)2.87 (1.51 to 5.49)8.83 (3.79 to 20.58)
Medication usage in previous 12 months
 Atopics0.93 (0.37 to 2.32)0.87 (0.59 to 1.27)0.87 (0.47 to 1.64)1.76 (0.75 to 4.16)
 Non-atopics0.85 (0.23 to 3.06)1.15 (0.72 to 1.85)1.80 (0.87 to 3.75)3.30 (1.40 to 7.81)
AHR (DRR >8.1)
 Atopics2.08 (0.91 to 4.73)0.72 (0.46 to 1.12)1.08 (0.56 to 2.08)1.01 (0.36 to 2.81)
 Non-atopics1.62 (0.34 to 7.70)1.03 (0.44 to 2.40)0.51 (0.05 to 3.88)No subjects in this group
  • BMI = body mass index; SOBOE = shortness of breath on exertion; AHR = airway hyperresponsiveness; DRR = dose response ratio.