Adjusted odds ratio for symptoms and airway hyperresponsiveness (AHR) in atopic and non-atopic subjects compared with a group of normal weight
|
Underweight (BMI <18.5) |
Overweight (BMI 25–29.9) |
Moderate obesity (BMI 30–34.9) |
Severe obesity (BMI ⩾35.0) | |
| Wheeze in last 12 months | ||||
| Atopics | 1.75 (0.80 to 3.82) | 0.97 (0.68 to 1.38) | 1.24 (0.70 to 2.20) | 1.71 (0.73 to 4.02) |
| Non-atopics | 0.57 (0.16 to 2.05) | 1.31 (0.86 to 2.00) | 2.37 (1.23 to 4.56) | 5.10 (2.27 to 11.45) |
| Recent asthma | ||||
| Atopics | 1.42 (0.59 to 3.45) | 0.99 (0.65 to 1.51) | 1.21 (0.62 to 2.35) | 1.43 (0.54 to 3.79) |
| Non-atopics | 0.38 (0.05 to 3.02) | 0.90 (0.47 to 1.72) | 2.21 (0.92 to 5.33) | 4.08 (1.52 to 10.98) |
| SOBOE | ||||
| Atopics | 2.34 (0.71 to 7.76) | 1.18 (0.76 to 1.84) | 1.89 (0.98 to 3.64) | 2.96 (1.15 to 7.62) |
| Non-atopics | 2.99 (0.86 to 10.31) | 1.92 (1.23 to 2.97) | 2.87 (1.51 to 5.49) | 8.83 (3.79 to 20.58) |
| Medication usage in previous 12 months | ||||
| Atopics | 0.93 (0.37 to 2.32) | 0.87 (0.59 to 1.27) | 0.87 (0.47 to 1.64) | 1.76 (0.75 to 4.16) |
| Non-atopics | 0.85 (0.23 to 3.06) | 1.15 (0.72 to 1.85) | 1.80 (0.87 to 3.75) | 3.30 (1.40 to 7.81) |
| AHR (DRR >8.1) | ||||
| Atopics | 2.08 (0.91 to 4.73) | 0.72 (0.46 to 1.12) | 1.08 (0.56 to 2.08) | 1.01 (0.36 to 2.81) |
| Non-atopics | 1.62 (0.34 to 7.70) | 1.03 (0.44 to 2.40) | 0.51 (0.05 to 3.88) | No subjects in this group |
BMI = body mass index; SOBOE = shortness of breath on exertion; AHR = airway hyperresponsiveness; DRR = dose response ratio.