Concentration required to provoke a 15% decrease in FEV0.5 (PC15FEV0.5), the corresponding response in LFOT parameters, and the magnitude of the response in SD units
| Patient no | PC15FEV0.5 | Raw | Iaw | G | H | η |
| 1 (H) | 1 | Br | – | – | – | – |
| 2 (D) | 1 | 12.61 (3.3) | –3.88 (–0.3) | –3.66 (–0.5) | 6.07 (0.3) | –8.85 (–0.3) |
| 3 (D) | 1 | 56.82 (7.8) | 95.76 (113.1) | 18.03 (4.4) | –19.95 (–2.5) | 46.31 (8.5) |
| 4 (H) | 16 | Br | – | – | – | – |
| 5 (D) | 0.5 | 44.53 (4.6) | 48.95 (6.9) | 20.86 (1.5) | 9.77 (3.3) | 6.54 (0.4) |
| 6 (D) | 4 | Br | – | – | – | – |
| 7 (D) | 1 | Br | – | – | – | – |
| 8 (H) | 0.25 | 76.09 (41.5) | 164.47 (22.3) | 62.57 (2.5) | –17.17 (–3.8) | 13.96 (2.6) |
| 9 (D) | Aw | Aw | – | – | – | – |
| 10 (H) | 16 | Br | – | – | – | – |
| 11 (H) | Aw | Aw | – | – | – | – |
| 12 (D) | Aw | Aw | – | – | – | – |
| 13 (D) | 2 | Br | – | – | – | – |
| 14 (H) | 16 | 82.67 (9.7) | 45.35 (11.1) | 149.03 (4.7) | –9.97 (–2.1) | 166.11 (4.6) |
| 15 (D) | 4 | Br | – | – | – | – |
| 16 (H) | 2 | 94.96 (24.5) | 221.96 (53.6) | 30.83 (1.6) | –7.66 (–1.2) | 41.54 (1.7) |
| 17 (D) | 1 | Br | – | – | – | – |
| Mean (SE) | 4.7(1.7) | 61.28 (12.22) (15.2 (6.1)) | 95.43 (34.31) (34.4 (17.5)) | 46.28 (22.36) (2.4 (0.8)) | –6.48 (4.94) (–1.0 (1.0)) | 44.26 (25.83) (2.9 (1.3)) |
PC15FEV0.5 is expressed in mg/ml; oscillatory mechanical parameters are shown as percentage increase from control with the magnitude of the response expressed in SD units (shown in parentheses).
Raw = airway resistance; Iaw = airway inertance; G = tissue damping; H = tissue elastance; η = tissue hysteresivity; Aw = infant awoke before completion of test; Br = pause in breathing of sufficient length to introduce the low frequency oscillation could not be induced; (H) = healthy; (D) = diseased.