Table 1

Demographic and pulmonary function data (all patients)

Frequent exacerbators (n=12) Infrequent exacerbators (n=28)
Age (years)67.3 (4.9)66.7 (7.2)
Male sex1-151 6 (50%)18 (64%)
Current smokers1-151 5 (42%)15 (54%)
Inhaled steroids1-151 10 (83%)1-150 13 (46%)
FEV1 (l)1.24 (0.48)1.19 (0.35)
FEV1 (%)52.3 (13.8)48.2 (15.4)
Response to inhaled β2agonists (ml)225 (130)175 (145)
FEV1/VC (%)43.5 (10.3)43.3 (12.6)
RV/TLC (%)118.8 (25.3)124.8 (22.2)
Kco (%)93.7 (33.8)91.0 (26.5)
  • FEV1 = forced expiratory volume in one second; VC = vital capacity; RV = residual volume; TLC = total lung capacity; Kco = carbon monoxide transfer coefficient.

  • Frequent exacerbators had suffered ⩾3 and infrequent exacerbators ⩽2 exacerbations in the previous 12 months.

  • 1-151 Clinical characteristics expressed as number (%); the remainder of the data are shown as mean (SD).

  • 1-150 Significant difference (p<0.05) in the proportion of patients receiving inhaled corticosteroids.