Baseline data
Case 1 | Case 2 | Case 3 | Case 4 | |
Age on presentation (years) | 27 | 46 | 44 | 35 |
Smoking history | ||||
Tobacco | 15 pack years | 7 pack years | 3 pack years | 2–5 cigars per day |
Marijuana | Several pipes per day | 2–3 joints per day | 2–3 joints per day | 2 joints per week |
Alpha1-antitrypsin (g/l) (NR 1.1–2.1) | 2.1 | 1.5 | 1.9 | 2.6 |
FVC (l) (% predicted) | 5.1 (106) | 4.6 (103) | 2.7 (72) | 2.9 (59) |
FEV1 (l) (% predicted) | 3.9 (97) | 3.3 (100) | 2.5 (78) | 1.8 (44) |
FEV1/FVC (%) | 77 | 72 | 94 | 62 |
Tlco mmol/kPa/min (% predicted) | 9.9 (96) | 5.9 (46) | 7.3 (72) | 3.9 (35) |
Kco mmol/kPa/min/l (% predicted) | 1.7 (89) | 1.4 (58) | 1.6 (78) | 1.0 (49) |