Blood gas tensions and lung function at baseline and after six (T6) and 12 months (T12) of non-invasive mechanical ventilation (NMV)
| Measurements | ANOVA | ||||
|---|---|---|---|---|---|
| Baseline | T6 | T12 | |||
| Po 2 (kPa) | 6.8 (1.3) | 9.0 (1.1) | 8.9 (1.2) | 0.0001 | |
| Pco 2 (kPa) | 7.6 (0.9) | 6.0 (0.5) | 6.0 (0.4) | 0.0001 | |
| pH | 7.37 (0.04) | 7.40 (0.02) | 7.39 (0.04) | 0.007 | |
| HCO3 – (mmol/l) | 32.1 (6.3) | 27.0 (2.8) | 25.9 (3.3) | 0.002 | |
| VC (l) | 1.1 (0.3) | 1.2 (0.3) | 1.2 (0.3) | 0.004 | |
| VC (% pred) | 41.5 (8.4) | 44.9 (7.7) | 44.3 (6.7) | 0.02 | |
| FEV1(l) | 0.8 (0.2) | 0.8 (0.2) | 0.9 (0.2) | 0.14 | |
| FEV1(% pred) | 72.2 (9.7) | 67.8 (10.4) | 71.7 (10.4) | 0.02 | |
| TLC (l) | 2.9 (0.7) | 3.0 (0.6) | 3.1 (0.7) | 0.20 | |
| TLC (% pred) | 60.8 (14.9) | 64.9 (13.4) | 63.7 (11.1) | 0.33 | |
Po 2, Pco 2 = arterial oxygen and carbon dioxide tensions; HCO3 – = bicarbonate; VC = vital capacity; FEV1 = forced expiratory volume in one second; TLC = total lung capacity.
Values are mean (SD).
Analysis of variance (ANOVA) for repeated measures was used as a global test (p <0.05 was considered significant).