Serum IgE concentration, lung function measures, and prevalence of respiratory symptoms and disease according to head circumference at birth
| Head circumference (cm) | Total | p for trend5-150 | |||||
|---|---|---|---|---|---|---|---|
| ⩽32 | -33 | -34 | >34 | ||||
| IgE | n=192 | n=240 | n=147 | n=139 | n=718 | ||
| Total IgE (IU/ml)5-160 | 29.5 | 24.4 | 31.3 | 42.3 | 30.5 (4.6) | 0.1 | |
| Prevalence of specific IgE (cat, mite or pollen) | 21.4% | 20.4% | 26.5% | 25.2% | 22.8% | 0.5 | |
| Lung function | n=194 | n=239 | n=150 | n=142 | n=725 | ||
| FEV1(l)5-165 | 3.09 | 3.13 | 3.09 | 3.06 | 3.09 (0.54) | 0.55-168 | |
| 5-150FVC (l)5-165 | 4.32 | 4.32 | 4.22 | 4.22 | 4.27 (0.65) | 0.25-168 | |
| FEV1/FVC5-165 | 0.717 | 0.726 | 0.735 | 0.730 | 0.727 (0.081) | 0.25-168 | |
| Respiratory symptoms and disease | n=251 | n=301 | n=178 | n=174 | n=904 | ||
| Wheeze | 13.9% | 11.0% | 11.8% | 9.8% | 11.7% | 0.6 | |
| Productive cough | 6.0% | 4.7% | 3.4% | 3.5% | 4.6% | 0.9 | |
| Obstructive airways disease | 8.7% | 17.9% | 21.9% | 13.2% | 18.0% | 0.7 | |