Serum IgE concentration, lung function measures, and prevalence of respiratory symptoms and disease according to birth weight
Birth weight (g) | Total | p for trend4-150 | |||||
---|---|---|---|---|---|---|---|
⩽2750 | -3250 | -3750 | >3750 | ||||
IgE | n=66 | n=240 | n=271 | n=149 | n=726 | ||
Total IgE (IU/ml)4-160 | 27.2 | 31.0 | 29.0 | 33.9 | 30.4 (4.6) | 1.0 | |
Prevalence of specific IgE (cat, mite or pollen) | 22.7% | 21.3% | 24.0% | 23.5% | 22.9% | 0.7 | |
Lung function | n=65 | n=242 | n=275 | n=151 | n=733 | ||
FEV1(l)4-165 | 3.11 | 3.08 | 3.09 | 3.14 | 3.10 (0.62) | 0.64-168 | |
FVC (l)4-165 | 4.30 | 4.26 | 4.27 | 4.35 | 4.29 (0.73) | 0.64-168 | |
FEV1/FVC4-165 | 0.722 | 0.728 | 0.724 | 0.727 | 0.725 (0.108) | 0.84-168 | |
Respiratory symptoms and disease | n=87 | n=302 | n=334 | n=189 | n=912 | ||
Wheeze | 13.8% | 12.3% | 12.0% | 9.5%% | 11.7% | 0.8 | |
Productive cough | 4.6% | 5.6% | 4.8% | 2.1% | 4.5% | 0.7 | |
Obstructive airways disease | 17.2% | 17.9% | 20.7% | 14.3% | 18.1% | 1.0 |