Effects of prenatal famine exposure expressed as differences (95% confidence intervals) according to prenatal exposure to famine compared with non-exposed people (born before or conceived after the famine)
| Exposed to famine | |||
|---|---|---|---|
| In late gestation | In mid gestation | In early gestation | |
| IgE | |||
| Relative differences3-150 | |||
| Serum concentration total IgE | −14.2% (−36.9 to 16.6) | −7.3% (−32.8 to 28.0) | −11.5% (−40.5 to 31.8) |
| Odds ratios3-160 | |||
| Prevalence of specific IgE | |||
| Cat | 1.2 (0.5 to 2.6) | 1.1 (0.5 to 2.6) | 1.0 (0.4 to 3.1) |
| House dust mite | 1.2 (0.7 to 2.1) | 1.2 ( 0.7 to 2.1) | 1.2 (0.6 to 2.4) |
| Pollen | 1.8 (1.0 to 3.3) | 0.7 (0.3 to 1.6) | 0.3 (0.1 to 1.3) |
| Any of these three | 1.3 (0.8 to 2.1) | 1.2 (0.7 to 2.0) | 0.8 (0.4 to 1.6) |
| Lung function | |||
| Absolute differences (95% CI)3-165 | |||
| FEV1 (l) | 0.03 (−0.08 to 0.14) | −0.06 (−0.17 to 0.06) | −0.06 (−0.20 to 0.08) |
| FVC (l) | 0.06 (−0.07 to 0.19) | −0.06 (−0.19 to 0.07) | −0.07 (−0.23 to 0.09) |
| FEV1/FVC (×100) | −0.4 (−2.1 to 1.4) | −0.3 (−2.1 to 1.6) | −0.6 (−2.9 to 1.6) |
| Respiratory symptoms and disease | |||
| Odds ratios (95% CI)3-160 | |||
| Wheeze | 0.9 (0.5 to 1.6) | 1.9 (1.2 to 3.2) | 1.2 (0.6 to 2.4) |
| Productive cough | 1.6 (0.7 to 3.7) | 2.2 (1.1 to 4.8) | 0.6 (0.1 to 2.7) |
| Obstructive airways disease | 0.9 (0.5 to 1.5) | 1.7 (1.1 to 2.6) | 1.5 (0.9 to 2.6) |