Serum IgE concentrations, lung function measures, and prevalence of respiratory symptoms and disease according to prenatal exposure to famine
| Born before famine | Exposed to famine | Conceived after famine | Mean (SD) | Missing observations | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| In late gestation | In mid gestation | In early gestation | |||||||||
| IgE | n=207 | n=119 | n=106 | n=64 | n=230 | n=726 | |||||
| Total IgE (IU/ml)2-150 | 31.0 | 27.2 | 28.9 | 27.9 | 33.1 | 30.4 (4.6) | 0 | ||||
| Prevalence of specific IgE | |||||||||||
| Cat | 7.2% | 6.7% | 6.6% | 6.3% | 4.3% | 6.1% | 0 | ||||
| House dust mite | 13.5% | 17.6% | 17.0% | 17.2% | 17.0% | 16.1% | 0 | ||||
| Pollen | 7.7% | 16.0% | 6.6% | 3.1% | 11.3% | 9.6% | 0 | ||||
| Any of these three | 18.8% | 26.9% | 24.5% | 18.8% | 24.8% | 22.9% | 0 | ||||
| Lung function | n=210 | n=118 | n=107 | n=67 | n=231 | n=733 | |||||
| FEV1(l)2-160 | 3.1 | 3.1 | 3.0 | 3.0 | 3.1 | 3.1 (0.6) | 0 | ||||
| FVC (l)2-160 | 4.3 | 4.4 | 4.2 | 4.2 | 4.2 | 4.3 (0.7) | 0 | ||||
| FEV1/FVC2-160 | 0.72 | 0.72 | 0.72 | 0.72 | 0.74 | 0.72 (0.1) | 0 | ||||
| Respiratory symptoms and disease | n=264 | n=140 | n=137 | n=87 | n=284 | n=912 | |||||
| Wheeze | 8.7% | 9.3% | 19.0% | 12.6% | 12.0% | 11.7% | 0 | ||||
| Productive cough | 4.2% | 5.8% | 8.0% | 2.3% | 3.2% | 4.5% | 4 | ||||
| Obstructive airways disease | 15.5% | 15.0% | 24.8% | 23.0% | 17.3% | 18.1% | 0 | ||||