Comparison of fibrotic changes between soluble E-selectin TG and non-TG mice
| Transgenic mice | Incidence | Grade | HOP (μmol/g) |
| (+) | 0/5 | 0/25 = 0 (0) | 23.8 (1.6) |
| (−) | 5/5 | 46/25 = 1.84 (0.08)2-150 | 44.6 (2.3)2-150 |
| Mean difference (95% CI) | 1.84 (1.6 to 2.0) | 20.9 (14 to 23) |
Degree of fibrosis (grade, mean (SE)) was evaluated according to Ekimoto's score.19 Mean (SE) levels of hydroxyproline (HOP, μmol/g) in the right lung were measured by modification of the method of Woessner.20
Mean differences (95% CI) of grade and hydroxyproline levels between TG(+) and TG(−) mice are shown.
↵2-150 p<0.001.