Table 2

Childhood infections in cases with adult onset wheeze and in subjects regrouped according to atopic status

Wheeze
(n=97)
Controls
(n=208)
Wheeze +
asthma
(n=23)
Wheeze +
cough/phlegm
(n=28)
Atopy positive
(n=154)
Atopy negative
(n=128)
Measles
No14  (14.7%)21  (10.3%)4  (17.4%)3  (11.1%)16  (10.7%)16  (12.6%)
⩽ age 330 (31.6%)74 (36.3%)4 (17.4%)8 (29.6%)50 (33.6%)44 (34.6%)
> age 351 (53.7%)109 (53.4%)15 (65.2%)16 (59.3%)83 (55.7%)67 (52.8%)
Rubella
No48 (50.5%)125 (61.3%)15 (65.2%)16 (59.3%)88 (58.3%)69 (54.8%)
⩽ age 36 (6.3%)12 (5.9%)0 (0%)2 (7.4%)12 (7.9%)5 (4.0%)
> age 341 (43.2%)67 (32.8%)8 (34.8%)9 (33.3%)51 (33.8%)52 (41.2%)
Pertussis
No81 (83.5%)163 (78.4%)17 (73.9%)25 (86.2%)130 (84.4%)98 (76.6%)
⩽ age 37 (7.2%)23 (11.0%)1 (4.3%)2 (6.9%)8 (5.2%)16 (12.5%)
> age 39 (9.3%)22 (10.6%)5 (21.7%)2 (6.9%)16 (10.4%)14 (10.9%)
Mumps
No61 (63.5%)130 (63.1%)15 (65.2%)17 (60.7%)96 (62.7%)81 (64.3%)
⩽ age 39 (9.4%)9 (4.4%)1 (4.4%)1 (3.6%)7 (4.6%)9 (7.1%)
> age 326 (27.1%)67 (32.5%)7 (30.4%)10 (35.7%)50 (32.7%)36 (28.6%)
Varicella
No38 (40.9%)76 (37.4%)3 (14.3%)13 (48.2%)57 (38.2%)50 (40.3%)
⩽ age 314 (15.0%)31 (15.3%)3 (14.3%)3 (11.1%)22 (14.8%)17 (13.7%)
> age 341 (44.1%)96 (47.3%)15 (71.4%)11 (40.7%)70 (47.0%)57 (46.0%)
Sum of all infections
None46 (51.1%)96 (49.5%)15 (71.4%)13 (54.2%)74 (51.7%)62 (52.1%)
Any 130 (33.3%)68 (35.1%)4 (19.0%)8 (33.3%)51 (35.7%)37 (31..1%)
Any 29 (10.0%)22 (11.3%)2 (9.6%)1 (4.2%)12 (8.4%)14 (11.8%)
3 or more5 (5.6%)8 (4.1%)0 (0%)2 (8.3%)6 (4.2%)6 (5.0%)
Sum of measles and pertussis
None60 (63.2%)118 (57.8%)19 (82.6%)17 (63.0%)95 (63.8%)74 (58.3%)
Either33 (34.7%)76 (37.3%)3 (13.0%)10 (37.0%)50 (33.6%)47 (37.0%)
Both2 (2.1%)10 (4.9%)1 (4.4%)0 (0%)4 (2.6%)6 (4.7%)
Sum of rubella, mumps and varicella
None 69 (76.7%)152 (77.5%)17 (81.0%)20 (83.4%)112 (77.2%)94 (79.0%)
Any of the 315 (16.7%)36 (18.4%)4 (19.0%)2 (8.3%)27 (18.6%)18 (15.1%)
2 or more6 (6.6%)8 (4.1%)0 (0%)2 (8.3%)6 (4.2%)7 (5.9%)