Table 1

Sibship structure in cases with adult onset wheeze and in subjects regrouped according to atopic status

Wheeze
(n=97)
Controls
(n=208)
Wheeze +
asthma
(n=23)
Wheeze +
cough/phlegm
(n=28)
Atopy positive (n=154) Atopy negative (n=129)
Number of older siblings
034  (35.0%)71  (34.1%)7  (30.4%)10  (35.7%)59  (38.4%)41  (31.8%)
128 (28.9%)62 (39.8%)8 (34.8%)9 (32.1%)43 (27.9%)37 (28.7%)
220 (20.6%)42 (20.2%)5 (21.7%)4 (14.3%)29 (18.8%)29 (22.5%)
3 or more15 (15.5%)33 (15.9%)3 (13.1%)5 (17.9%)23 (14.9%)22 (17.0%)
Number of younger siblings
036 (37.1%)83 (40.0%)12 (52.2%)8 (28.6%)57 (37.0%)54 (41.8%)
135 (36.1%)67 (32.2%)9 (39.1%)8 (28.6%)46 (29.9%)49 (38.0%)
215 (15.5%)34 (16.3%)2 (8.7%)6 (21.4%)32 (20.8%)12 (9.3%)
3 or more11 (11.3%)24 (11.5%)0 (0%)6 (21.4%)19 (12.3%)14 (10.9%)1-150
Total number of siblings
08 (8.3%)17 (8.2%)4 (17.4%)1 (3.6%)13 (8.4%)11 (8.5%)
128 (28.9%)52 (25.0%)7 (30.4%)6 (21.4%)38 (24.7%)34 (26.4%)
219 (19.6%)55 (26.4%)6 (26.2%)6 (21.4%)39 (25.3%)32 (24.8%)
321 (21.6%)45 (21.6%)3 (13.0%)8 (28.6%)32 (20.8%)30 (23.2%)
4 or more21 (21.6%)39 (18.8%)3 (13.0%)7 (25.0%)32 (20.8%)22 (17.1%)
  • 1-150 p⩽0.05 (χ2 tests of independence).