Table 1

Mean (SE) baseline values of heart rate, QTc interval, systolic and diastolic blood pressure, plasma potassium concentration and plasma glucose concentration on the seven study days

FormoterolSalmeterolPlacebo
24 μg48 μg 96 μg100 μg 200 μg 400 μg
Heart rate (bpm)55.6 (1.7)56 (1.6)54.8 (1.4)55.6 (1.4)56 (1.7)55.9 (1.4)56 (1.4)
QTc interval (ms)400 (3.5)397 (3.6)397 (3.6)400 (3.2)396 (4.1)403 (2.8)398 (3.1)
Systolic BP (mmHg)115 (3.1)118 (3.3)116 (3.6)114 (2.5)114 (2.7)115 (3.5)113 (3)
Diastolic BP (mmHg)72 (2.6)76 (2)77 (2.7)74 (2.1)74 (1.8)75 (2.6)74 (2.4)
Plasma K+ (mmol/l)4.1 (0.1)4 (0.1)4 (0.1)4. (0.1)4 (0.1)4 (0.1)4.1 (0.1)
Plasma glucose (mmol/l)5.3 (0.2)5.3 (0.2)5.2 (0.1)5.4 (0.2)5.3 (0.2)5.3 (0.1)5.4 (0.1)