Table 2

Mean (SE) values of maximum pressures, spirometric parameters, serum digoxin, and pain before and after surgery in the two group of subjects

DigoxinPlacebo
Pimax (kPa)
 Pre-op7.72 (0.86)9.62 (0.59)
 Post-B5.52 (0.63)6.12 (0.41)
 Post-A6.77 (0.9)6.38 (0.37)
 Δ (post-A/post-B)1.26 (0.4)2-150 0.26 (0.17)
 ΔPimax1.01 (95% CI 0.28 to 2.2)2-150
Pemax (kPa)
 Pre-op10.60 (1.54)10.24 (1.19)
 Post-B4.41 (0.35)5.52 (0.62)
 Post-A5.70 (0.74)5.28 (0.40)
 Δ (post-A/post-B)1.29 (0.5)2-150 0.24 (0.12)
 ΔPemax1.05 (95% CI 0.04 to 2.4)2-150
FEV1 (% pred)
 Pre-op111 (3.8)115 (6.1)
 Post-B73.4 (4.3)77 (4.8)
 Post-A75.1 (3.8)76.3 (4.5)
FVC (% pred)
 Pre-op112 (3.5)107 (4.7)
 Post-B70 (3.2)68 (3.0)
 Post-A73 (5.1)71 (1.8)
FEV1/FVC (%)
 Pre-op80 (1.3)83 (1.7)
 Post-B77 (2.7)79 (2.2)
 Post-A75 (3.8)82 (3.1)
VC (% pred)
 Pre-op117 (4.7)108 (4.3)
 Post-B75 (6.1)82 (3.5)
 Post-A77 (5.8)84 (3.6)
Serum digoxin (ng/ml)
 Post-A1.5 (0.67)
Pain (VAS)
 Post-B3.3 (1.1)3.2 (2.1)
 Post-A4.2 (2.3)3.7 (1.7)
  • 2-150 Statistically significant differences.

  • Δ(post-A/post-B) = changes in pressure after intervention in the same group; ΔPimax, ΔPemax = difference in changes in pressures after intervention between digoxin and placebo; pre-op = preoperative; post = postoperative; B = before digoxin or placebo; A = after digoxin or placebo; VAS = visual analogue scale.