Table 2

Selected measurements on breathing oxygen and NO/oxygen

Baseline
Mean (SE)
NO
Mean (SE)
Difference
Mean (95% CI)
p value
Pao 2 (kPa) 11.3 (0.6) 11.5 (0.6)  0.2 (−1.2 to +1.5)>0.5
Paco 2(kPa)  6.2 (0.5)  6.2 (0.4)  0.2 (−0.93 to +0.97)>0.5
PAP (torr) 26.1 (2.5) 25.1 (2.8)  1.0 (−3.1 to +5.1)>0.5
Systolic PAP (torr)  35.5 (3.5) 36.0 (4.3)  0.5 (−5.3 to +6.3)>0.5
P wedge (torr) 13.8 (1.7) 14.3 (1.4)  0.5 (−3.4 to +4.3)>0.5
CO (l/min)  5.9 (0.4)  8.2 (1.1)  2.3 (+0.3 to +4.3)0.0262-150
PVR (dyne.s.cm–3)183.1 (36.7)137.2 (34.2)−45.9 (−2.5 to –89.3)0.042-150
Vd/Vt (%) 50.1 (2.5) 52.6 (1.9)  2.1 (−2.5 to +6.7)0.35
Qs/Qt (%)  7.5 (1.7) 10.9 (0.9)  3.4 (−0.3 to +7.1)0.07
  • 2-150 Statistically significant difference.

  • Baseline = measurements breathing supplemental oxygen with air alone prior to administration of NO; NO = values obtained after 24 hours of breathing NO; difference = values on NO minus baseline values; Pao 2, Paco 2 = arterial oxygen and carbon dioxide tensions; PAP = pulmonary artery pressure; P wedge = pulmonary wedge pressure; CO = cardiac output; PVR = pulmonary vascular resistance; Vd/Vt = dead space/tidal volume ratio; Qs/Qt = venous admixture ratio.