Summary of the significant differences in cellular parameters between patients with COPD and healthy individuals
| COPD | Healthy controls | p value | |
| Biopsy specimen | |||
| EG2+ (cells/mm2) | 40 (0–190) | 5 (0–40) | 0.049 |
| CD68+ (cells/mm2) | 1115 (330–2920) | 590 (450–1580) | 0.03 |
| CD3+ (cells/mm2) | 935 (170–2240) | 385 (210–1520) | 0.07 |
| CD4+ (cells/mm2) | 560 (100–1320) | 260 (60–870) | 0.07 |
| Sputum | |||
| Neutrophils (%) | 77 (29–94) | 36 (18–60) | 0.001 |
| Eosinophils (%) | 1.2 (0–8.5) | 0.2 (0–3.1) | 0.008 |
| IL-8 (ng/ml) | 15.4 (3.5–1300) | 4.6 (3.1–7.7) | 0.001 |
| ECP (ng/ml) | 838 (115–23760) | 121 (35–218) | 0.001 |
| BAL fluid | |||
| Eosinophils (%) | 0.4 (0–1.7) | 0.2 (0–0.5) | 0.03 |
| IL-8 (pg/ml) | 35.8 (0–2639) | 8.2 (0–56.6) | 0.06 |
Data are medians (ranges).
ECP = eosinophil cationic protein; IL = interleukin; BAL = bronchoalveolar lavage.