Comparison of selected variables between groups.
| Controls Mean (SD) | Patients Mean (SD) | |||
|---|---|---|---|---|
| Vt (l) | 0.68 (0.13) | 0.68 (0.16) | ||
| Ti(s) | 1.57 (0.48) | 1.47 (0.35) | ||
| Te (s) | 2.43 (1.02) | 2.26 (0.55) | ||
| Tt (s) | 4.03 (1.48) | 3.75 (0.82) | ||
| f (bpm) | 16.6 (3.6) | 17.4 (4.3) | ||
| V˙(l/min) | 10.9 (2.1) | 11.2 (2.2) | ||
| Petco2 (kPa) | 5.28 (0.40) | 4.89 (0.47)2-160 | ||
| Paco 2(kPa) | 5.27 (0.38) | 4.96 (0.43)2-150 | ||
| a-ET (kPa) | −0.13 (0.24) | 0.04 (0.20)2-160 | ||
| Pao 2 (kPa) | 13.7 (1.07) | 14.4 (1.05) | ||
| pH | 7.38 (0.02) | 7.39 (0.03) | ||
| HCO3 − (/mmol) | 22.9 (1.27) | 22.5 (1.11) | ||
| BE (/mmol) | −1.28 (1.47) | −1.71 (1.47) | ||
| FEV1 (% pred) | 101.7 (16.5) | 97.6 (11.6) | ||
| FEV1/VC (% pred) | 76.1 (20.8) | 76.2 (7.4) | ||
| PEF (% pred) | 107.1 (13.3) | 97.8 (13.2)2-150 | ||
| Tlco (% pred) | 122.2 (15.8) | 128.8 (15.7) | ||
| Kco (% pred) | 108.5 (11.6) | 105.4 (13.0) | ||
| TLC (% pred) | 95.6 (12.1) | 102.6 (10.2) | ||
| RV (% pred) | 86.6 (22.9) | 108.3 (31.5)2-150 | ||
| PC20 (GM mg/ml) | n=6; 12.4 (4.6) | 1.65 (1.56) | ||
| n=11; >32 | ||||
| Median (range) | Median (range) | |||
| Eosinophils (%) | 0 (0–3.2) | 3 (0–27)2-160 | ||
| BDI | 2 (0–9) | 2 (0–10) | ||
| Anxiety state | 23 (20–48) | 31 (21–58)2-150 | ||
| Anxiety trait | 28 (20–50) | 36 (21–58) | ||
Vt = tidal volume; Ti = inspiratory time; Te = expiratory time; Tt = cycle duration; f = respiratory frequency; V˙ = minute ventilation; Petco 2 = end tidal Pco 2; Paco 2 = arterial Pco 2; a–ET = difference between arterial and end tidal Pco 2, Pao 2 = arterial Po 2; pH = acidity of arterial blood; HCO3 − = bicarbonate of arterial blood; BE = base excess of arterial blood; FEV1 = forced expired volume in one second; FEV1/VC = ratio of FEV1 to vital capacity; PEF = peak expiratory flow; Tlco = single breath carbon monoxide gas transfer; Kco = gas transfer corrected for total lung volume; TLC = total lung capacity; RV = residual volume; PC20 = concentration of methacholine at 20% reduction of FEV1; BDI = Beck Depression Inventory scores; Anxiety state and trait = scores from Spielberger STAI.
↵2-150 p<0.05,
↵2-160 p<0.01 for comparison between groups.