Characteristics of study subjects in relation to the functional status
| Class D (n=10) | Class C (n=28) | Class B (n=15) | Class A (n=4) | |
| Age (years) | 65 (8)ab | 69 (5)a | 62 (8)b | 56 (9)b |
| Sex (M/F) | 7/3 | 24/4 | 14/1 | 4/0 |
| BMI (kg/m2) | 28.0 (7.7) | 23.5 (3.9) | 25.8 (4.7) | 22.2 (2.8) |
| FEV1(l) | 0.68 (0.15)a | 1.02 (0.36)b | 1.20 (0.30)b | 1.56 (0. 76)b |
| FEV1(% pred) | 29 (9)a | 39 (16)ab | 43 (14)b | 48 (17)ab |
| FVC (l) | 1.72 (0.42)a | 2.68 (0.62)b | 2.81 (0.62)b | 3.04 (0.49)b |
| FVC (% pred) | 48 (11)a | 68 (15)b | 68 (14)b | 69 (13)b |
| FEV1/FVC (%) | 41 (11) | 38 (10) | 43 (8) | 52 (25) |
| FRC (% pred) | 172 (30)a | 150 (35)ab | 141 (16)ab | 122 (28)b |
| IC (% pred) | 55 (16)a | 78 (17)b | 73 (13)ab | 89 (8)b |
| TLC (% pred) | 123 (16) | 119 (22) | 113 (11) | 109 (20) |
| Tlco (% pred) | 65 (35) | 59 (17) | 70 (26) | 90 (31) |
| Po 2 (kPa) | 9.6 (2.3) | 10.2 (1.6) | 11.2 (1.5) | 11.7 (0.5) |
| Sao 2(%) | 93 (8) | 96 (2) | 97 (1) | 98 (1) |
| pH | 7.38 (0.05)a | 7.42 (0.03)b | 7.42 (0.03)ab | 7.44 (0.01}b |
| Pco 2 (kPa) | 6.5 (1.1)a | 5.5 (0.8)b | 5.4 (0.9)b | 4.9 (0.3)b |
| Lactate (mmol/l) | 1.06 (0.70) | 1.02 (0.70) | 0.80 (0.41) | 0.95 (0.22) |
Values are mean (SD). Values followed by different superscript letters are significantly different. BMI = body mass index; FEV1 = forced expiratory volume in one second; FVC = forced vital capacity; FRC = functional residual capacity; IC = inspiratory capacity; TLC = total lung capacity; Tlco = carbon monoxide transfer factor; Po 2, Pco 2 = carbon monoxide and oxygen gas tensions.